Association of FTO common variant (rs9939609) with body fat in Turkish individuals
نویسندگان
چکیده
منابع مشابه
The common rs9939609 gene variant of the fat mass- and obesity-associated gene FTO is related to fat cell lipolysis.
We investigated the rs9939609 single nucleotide polymorphism of the FTO gene in relation to fat cell function and adipose tissue gene expression in 306 healthy women with a wide range in body mass index (18-53 kg/m(2)). Subcutaneous adipose tissue biopsies were taken for fat cell metabolism studies and in a subgroup (n = 90) for gene expression analyses. In homozygous carriers of the T-allele, ...
متن کاملCommon Variant of FTO Gene, rs9939609, and Obesity in Pakistani Females
Numerous studies confirmed the association of FTO (fat mass and obesity associated gene) common variant, rs9939609, with obesity in European populations. However, studies in Asian populations revealed conflicting results. We examined the association of rs9939609 variant of FTO gene with obesity and obesity-related anthropometric and metabolic parameters in Pakistani population. Body weight, hei...
متن کاملInfluences of the Common FTO rs9939609 Variant on Inflammatory Markers Throughout a Broad Range of Body Mass Index
BACKGROUND A recent study reported that the fatness associated A-allele of FTO rs9939609 increased plasma high sensitivity C-reactive protein (hs-CRP) levels independent of fatness. We aimed to investigate if this gene variant had fatness-independent effects on plasma hs-CRP and 10 additional circulating obesity-related adipokines throughout a broad range of body mass index (BMI) among Danish m...
متن کاملCommon Variant rs9939609 in Gene FTO Confers Risk to Polycystic Ovary Syndrome
BACKGROUND Fat mass and obesity-associated gene (FTO) has been associated with obesity, especially the common variant rs9939609. Polycystic ovary syndrome (PCOS) is a complex endocrine-metabolic disorder and over 50% of patients are overweight/obese. Thus FTO is a potential candidate gene for PCOS but their relationship is confusing and remains to be clarified in different population with a lar...
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ژورنال
عنوان ژورنال: Lipids in Health and Disease
سال: 2019
ISSN: 1476-511X
DOI: 10.1186/s12944-019-1160-y